Juglone, CAS [[481-39-0]]

Product Overview

• Article Name: Juglone, CAS [[481-39-0]]
• Biozol Catalog Number: BYT-ORB1303312
• Supplier Catalog Number: orb1303312
• Alternative Catalog Number: BYT-ORB1303312-10, BYT-ORB1303312-100, BYT-ORB1303312-25, BYT-ORB1303312-5, BYT-ORB1303312-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: DNA Synthesis, DNASynthesis, 5-Hydroxy-1,4-naphthoquinone, antimicrobial, Bacterial, black, Inhibitor, Juglone, inhibit, RNA polymerase, RNA Synthesis, RNASynthesis, walnut, Regianin, Pigment, Yellow

Product Description

Juglone (Regianin, CAS 481-39-0) is a natural compound that potently inhibits Pin1 and other parvulin-family PPIases (Ki = 55.9 nM). It also blocks eukaryotic RNA polymerases (IC50 2-7 µM) and has demonstrated in vivo activity in attenuating kidney fibrosis in rodent models, acting through both Pin1-dependent and independent mechanisms.

Product Properties

• Molecular Weight: 174.15
• Purity: 99.24% (May vary between batches)
• CAS Number: [481-39-0]
• Formula: C10H6O3
• Target: TLR,DNA/RNA Synthesis,Antibacterial,NF-kappaB,Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:5.56 mg/mL (31.93 mM),Ethanol:15 mg/mL (86.13 mM)