Thalidomide-NH-CH2-COOH, CAS [[927670-97-1]]

Product Overview

• Article Name: Thalidomide-NH-CH2-COOH, CAS [[927670-97-1]]
• Biozol Catalog Number: BYT-ORB1303328
• Supplier Catalog Number: orb1303328
• Alternative Catalog Number: BYT-ORB1303328-1, BYT-ORB1303328-10
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Cereblon, cereblon, CRBN, E3 ligase-recruiting Moiety, (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine, 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid, Inhibitor, LigandforE3Ligase, Ligands for E3 Ligase, Ligand for E3 Ligase, inhibit, Thalidomide, Thalidomide NH CH2 COOH, ThalidomideNHCH2COOH, Thalidomide-NH-CH-2-COOH, Thalidomide-NH-CH2-COOH

Product Description

This compound is a synthesized cereblon E3 ligase ligand-linker conjugate, incorporating a thalidomide derivative connected to a glycine linker. It serves as a key component in the development of PROTACs for targeted protein degradation, a strategy widely used in vitro and in vivo for probing disease-related protein functions.

Product Properties

• Molecular Weight: 331.28
• Purity: 96.38% (May vary between batches)
• CAS Number: [927670-97-1]
• Formula: C15H13N3O6
• Target: Apoptosis,Autophagy,E3 Ligase Ligand-Linker Conjugates,Ligands for E3 Ligase

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.02 mM),DMSO:42.5 mg/mL (128.29 mM)