(S)-Indoximod (L-Abrine) is a competitive IDO inhibitor that reduces Foxp3 expression and exhibits antitumor activity in mouse LLC allograft models. In vitro, it demonstrates antiproliferative effects against LLC cells. This small molecule is a research tool for studying immunomodulation and cancer therapy in both cellular and animal systems.
Molecular Weight:
218.25
Purity:
99.69% (May vary between batches)
CAS Number:
[21339-55-9]
Formula:
C12H14N2O2
Target:
Indoleamine 2,3-Dioxygenase (IDO),IDO
Application Notes:
Solubility: DMSO:Slightly soluble,0.1 M NaOH:10 mg/mL (45.82 mM)
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