CFMTI is a highly potent and selective allosteric antagonist of metabotropic glutamate receptor 1 (mGluR1), exhibiting an IC50 of 2.6 nM with over 2000-fold selectivity versus mGluR5. This tool compound is valuable for investigating mGluR1 function in neurological research, including studies on pain, neurodegeneration, and synaptic plasticity in both cellular and animal models.
Molecular Weight:
349.36
Purity:
98.61% (May vary between batches)
CAS Number:
[864864-17-5]
Formula:
C19H16FN5O
Target:
GluR
Application Notes:
Solubility: DMSO:4.62 mg/mL (13.22 mM)
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