Tomivosertib, CAS [[1849590-01-7]]

Product Overview

• Article Name: Tomivosertib, CAS [[1849590-01-7]]
• Biozol Catalog Number: BYT-ORB1304174
• Supplier Catalog Number: orb1304174
• Alternative Catalog Number: BYT-ORB1304174-1, BYT-ORB1304174-5, BYT-ORB1304174-1, BYT-ORB1304174-10, BYT-ORB1304174-25, BYT-ORB1304174-50, BYT-ORB1304174-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: PD-L1, PDL1, Tomivosertib, PD-1/PD-L1, PD1/PDL1, PD1, PD-1, Mitogen activated protein kinase interacting kinase, MNK, MNK1, MNK2, Inhibitor, inhibit, MAP kinase interacting kinase, MAPK interacting kinase, eFT 508, eFT508, eFT-508

Product Description

Tomivosertib (eFT508) is a highly selective, potent dual inhibitor of MNK1 and MNK2 kinases, exhibiting IC50 values in the low nanomolar range. It is widely used in preclinical research to investigate MNKs role in oncogenesis and immune modulation, demonstrating antitumor activity in both cellular assays and in vivo animal models.

Product Properties

• Molecular Weight: 340.38
• Purity: 99.72% (May vary between batches)
• CAS Number: [1849590-01-7]
• Formula: C17H20N6O2
• Target: MNK,PD-1/PD-L1

Application Notes

• Application Notes: Solubility: H2O:<1 mg/mL,DMSO:11 mg/mL (32.32 mM),Ethanol:<1 mg/mL