SZL P1-41, CAS [[222716-34-9]]

Product Overview

• Article Name: SZL P1-41, CAS [[222716-34-9]]
• Biozol Catalog Number: BYT-ORB1304331
• Supplier Catalog Number: orb1304331
• Alternative Catalog Number: BYT-ORB1304331-1, BYT-ORB1304331-10, BYT-ORB1304331-100, BYT-ORB1304331-2, BYT-ORB1304331-25, BYT-ORB1304331-5, BYT-ORB1304331-50, BYT-ORB1304331-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: E1/E2/E3 Enzyme, E1 Enzyme, E2 conjugating enzyme, E1Enzyme, E2 Enzyme, E2Enzyme, E3 Enzyme, E1 activating enzyme, Apoptosis, E3Enzyme, E3 ligating enzyme, Inhibitor, inhibit, SZL P1 41, SZL P141, SZL P-1-41, SZL P1-41, skp2, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme

Product Description

SZL P1-41 is a selective skp2 inhibitor that disrupts Skp2-SCF E3 ligase assembly and activity, blocking p27 and Akt ubiquitination in vitro and in vivo. It induces cell senescence, inhibits glycolysis, and demonstrates antitumor efficacy by suppressing the survival of cancer and cancer stem cells in various preclinical models.

Product Properties

• Molecular Weight: 420.52
• Purity: >99.99% (May vary between batches)
• CAS Number: [222716-34-9]
• Formula: C24H24N2O3S
• Target: E1/E2/E3 Enzyme,Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:1.05 mg/mL (2.5 mM)