Bicuculline, CAS [[485-49-4]]

Catalog Number: BYT-ORB1304933
Article Name: Bicuculline, CAS [[485-49-4]]
Biozol Catalog Number: BYT-ORB1304933
Supplier Catalog Number: orb1304933
Alternative Catalog Number: BYT-ORB1304933-1, BYT-ORB1304933-10, BYT-ORB1304933-100, BYT-ORB1304933-25, BYT-ORB1304933-50
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: Bicuculline, (+)-Bicuculline, AHP, alkaloid, d-Bicuculline, convulsant, competitive, inhibit, neurotransmitter, Inhibitor, GABAR, GABA Receptor, GABAReceptor, Gamma-aminobutyric acid Receptor, potassium, gamma-Aminobutyric acid Receptor
Bicuculline is a natural alkaloid that acts as a competitive GABAA receptor antagonist (IC50 = 2 µM) and a blocker of SK potassium channels. It is widely utilized in neuroscience research to induce seizures in animal models and to study synaptic inhibition and neuronal excitability in vitro.
Molecular Weight: 367.35
Purity: 99.99% (May vary between batches)
CAS Number: [485-49-4]
Formula: C20H17NO6
Target: GABA Receptor
Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.44 mM),DMSO:16.67 mg/mL (45.38 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble)