Bicuculline, CAS [[485-49-4]]
Catalog Number:
BYT-ORB1304933
Product Overview
Article Name:
Bicuculline, CAS [[485-49-4]]
Biozol Catalog Number:
BYT-ORB1304933
Supplier Catalog Number:
orb1304933
Alternative Catalog Number:
BYT-ORB1304933-1, BYT-ORB1304933-10, BYT-ORB1304933-100, BYT-ORB1304933-25, BYT-ORB1304933-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
Bicuculline, (+)-Bicuculline, AHP, alkaloid, d-Bicuculline, convulsant, competitive, inhibit, neurotransmitter, Inhibitor, GABAR, GABA Receptor, GABAReceptor, Gamma-aminobutyric acid Receptor, potassium, gamma-Aminobutyric acid Receptor
Product Description
Bicuculline is a natural alkaloid that acts as a competitive GABAA receptor antagonist (IC50 = 2 µM) and a blocker of SK potassium channels. It is widely utilized in neuroscience research to induce seizures in animal models and to study synaptic inhibition and neuronal excitability in vitro.
Product Properties
Molecular Weight:
367.35
Purity:
99.99% (May vary between batches)
CAS Number:
[485-49-4]
Formula:
C20H17NO6
Target:
GABA Receptor
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.44 mM),DMSO:16.67 mg/mL (45.38 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble)