Firibastat, CAS [[648927-86-0]]

Product Overview

• Article Name: Firibastat, CAS [[648927-86-0]]
• Biozol Catalog Number: BYT-ORB1304935
• Supplier Catalog Number: orb1304935
• Alternative Catalog Number: BYT-ORB1304935-1, BYT-ORB1304935-10, BYT-ORB1304935-100, BYT-ORB1304935-25, BYT-ORB1304935-5, BYT-ORB1304935-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: QGC 001, QGC001, QGC-001, Inhibitor, inhibit, hypertensive, Firibastat, Aminopeptidase A, Aminopeptidase, angiotensin, brain, blood, RB150, RB-150, RB 150, pressure

Product Description

Firibastat (RB150) is an orally active, brain-penetrating prodrug of EC33 and a first-in-class aminopeptidase A (APA) inhibitor (Ki=200 nM). It selectively blocks the conversion of angiotensin-II to angiotensin-III in the brain, demonstrating antihypertensive effects in rodent models of hypertension and serving as a key research tool for studying the brain renin-angiotensin system.

Product Properties

• Molecular Weight: 368.51
• Purity: 99.88% (May vary between batches)
• CAS Number: [648927-86-0]
• Formula: C8H20N2O6S4
• Target: Aminopeptidase

Application Notes

• Application Notes: Solubility: H2O:30 mg/mL (81.41 mM)