5-Hydroxy-1-methylhydantoin (HD-003) is a creatinine-derived antioxidant and hydroxyl radical scavenger studied for renal and vascular protection. Research indicates it suppresses high glucose-induced B2KR expression and attenuates bradykinin-driven MAPK/CTGF signaling in VSMCs, demonstrating potential in models of diabetic nephropathy and vascular remodeling.
Molecular Weight:
130.1
Purity:
99.99% (May vary between batches)
CAS Number:
[84210-26-4]
Formula:
C4H6N2O3
Target:
Bradykinin Receptor,ROS,Reactive Oxygen Species
Application Notes:
Solubility: DMSO:60 mg/mL (461.18 mM)
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