NIBR-0213, CAS [[1233332-14-3]]

Product Overview

• Article Name: NIBR-0213, CAS [[1233332-14-3]]
• Biozol Catalog Number: BYT-ORB1304983
• Supplier Catalog Number: orb1304983
• Alternative Catalog Number: BYT-ORB1304983-1, BYT-ORB1304983-1, BYT-ORB1304983-10, BYT-ORB1304983-25, BYT-ORB1304983-5
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: autoimmune, encephalomyelitis, Inhibitor, inhibit, LPL Receptor, LPLReceptor, NIBR 0213, NIBR0213, NIBR-0213, Lysophospholipid Receptor, S1PR1, S1P1

Product Description

NIBR-0213 is a potent, competitive, and selective S1P1 receptor antagonist, demonstrating IC50 values of 2.0 nM (human) and 2.3 nM (rat) in GTPgammaS binding assays. It shows efficacy in the experimental autoimmune encephalomyelitis (EAE) model, supporting its use in researching multiple sclerosis and other autoimmune disorders.

Product Properties

• Molecular Weight: 464.98
• Purity: 99.34% (May vary between batches)
• CAS Number: [1233332-14-3]
• Formula: C27H29ClN2O3
• Target: LPL Receptor

Application Notes

• Application Notes: Solubility: DMSO:55 mg/mL (118.28 mM)