NGB 2904 is a highly selective dopamine D3 receptor antagonist with a Ki of 1.4 nM, exhibiting over 150-fold selectivity versus the D2 receptor. It potently inhibits quinpirole-stimulated mitogenesis (IC50 = 6.8 nM) and is a valuable research tool for investigating D3 receptor function in neuropsychiatric disorders and addiction models, both in vitro and in vivo.
Molecular Weight:
494.46
Purity:
99.35% (May vary between batches)
CAS Number:
[189060-98-8]
Formula:
C28H29Cl2N3O
Target:
5-HT Receptor,Dopamine Receptor
Application Notes:
Solubility: DMSO:16.25 mg/mL (32.86 mM)
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