MI-2-2, CAS [[1454920-20-7]]

Product Overview

• Article Name: MI-2-2, CAS [[1454920-20-7]]
• Biozol Catalog Number: BYT-ORB1305000
• Supplier Catalog Number: orb1305000
• Alternative Catalog Number: BYT-ORB1305000-1, BYT-ORB1305000-5
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: MI 22, MI22, MI-22, MI-2-2, MI 2 2, inhibit, Epigenetic Reader Domain, Inhibitor, Hoxa9 expression, HistoneMethyltransferase, Histone Methyltransferase, leukemia, Menin-MLL, menin-MLL interaction, differentiation, cell proliferation

Product Description

MI-2-2 is a potent, cell-permeable small molecule inhibitor that disrupts the menin-MLL protein-protein interaction, exhibiting an IC50 of 46 nM and a Kd of 22 nM for menin. It is a valuable chemical probe for studying menin-dependent transcriptional regulation in leukemia research, applicable in both cellular and biochemical assays.

Product Properties

• Molecular Weight: 415.5
• Purity: 99.65% (May vary between batches)
• CAS Number: [1454920-20-7]
• Formula: C17H20F3N5S2
• Target: Epigenetic Reader Domain,Histone Methyltransferase

Application Notes

• Application Notes: Solubility: DMSO:Soluble