JW 67, CAS [[442644-28-2]]

Product Overview

• Article Name: JW 67, CAS [[442644-28-2]]
• Biozol Catalog Number: BYT-ORB1305788
• Supplier Catalog Number: orb1305788
• Alternative Catalog Number: BYT-ORB1305788-1,BYT-ORB1305788-2,BYT-ORB1305788-5,BYT-ORB1305788-10,BYT-ORB1305788-25,BYT-ORB1305788-50,BYT-ORB1305788-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: GSK-3b, Inhibitor, JW67, JW-67, JW 67, multiprotein, inhibit, CK1, complex, beta-catenin, betacatenin, bcatenin, AXIN, APC, Wnt/beta-catenin, Wnt/betacatenin, Wnt/b-catenin, Wnt, betacatenin, beta-catenin

Product Description

JW 67 is a small molecule inhibitor of the canonical Wnt/beta-catenin pathway. It acts by rapidly decreasing active beta-catenin levels, leading to the downregulation of target genes such as AXIN2, SP5, and NKD1. This inhibitor is a valuable tool for studying Wnt signaling in both cellular assays and in vivo disease models, including cancer and stem cell research.

Product Properties

• Molecular Weight: 394.38
• Purity: 99.02% (May vary between batches)
• CAS Number: [442644-28-2]
• Formula: C21H18N2O6
• Target: Wnt/beta-catenin

Application Notes

• Application Notes: Solubility: DMSO:60 mg/mL (152.14 mM),10% DMSO+90% Saline:2.5 mg/mL (6.34 mM)