Belzutifan, CAS [[1672668-24-4]]

Product Overview

• Article Name: Belzutifan, CAS [[1672668-24-4]]
• Biozol Catalog Number: BYT-ORB1307837
• Supplier Catalog Number: orb1307837
• Alternative Catalog Number: BYT-ORB1307837-1,BYT-ORB1307837-10,BYT-ORB1307837-100,BYT-ORB1307837-200,BYT-ORB1307837-25,BYT-ORB1307837-5,BYT-ORB1307837-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Belzutifan, Inhibitor, inhibit, MK 6482, MK6482, MK-6482, HIF-PH, HIFs, HIF-2alpha, HIF/HIF Prolyl-Hydroxylase, Hypoxia-inducible factors, PT 2977, PT2977, PT-2977

Product Description

Belzutifan (MK-6482) is a potent and selective oral HIF-2alpha inhibitor with an IC50 of 9 nM, developed for clear cell renal cell carcinoma (ccRCC) research. It demonstrates efficacy in both in vitro assays and in vivo xenograft models, supporting its investigation in oncology and hypoxia-related pathways.

Product Properties

• Molecular Weight: 383.34
• Purity: 99.88% (May vary between batches)
• CAS Number: [1672668-24-4]
• Formula: C17H12F3NO4S
• Target: HIF/HIF Prolyl-Hydroxylase,HIF

Application Notes

• Application Notes: Solubility: DMSO:50.5 mg/mL (131.74 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.22 mM)