PS210, CAS [[1221962-86-2]]

Product Overview

• Article Name: PS210, CAS [[1221962-86-2]]
• Biozol Catalog Number: BYT-ORB1307839
• Supplier Catalog Number: orb1307839
• Alternative Catalog Number: BYT-ORB1307839-1,BYT-ORB1307839-10,BYT-ORB1307839-100,BYT-ORB1307839-2,BYT-ORB1307839-25,BYT-ORB1307839-5,BYT-ORB1307839-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: a-B, Arg131, inhibit, Lys76, Inhibitor, helix, Thr148, pocket, PDK-1, PDK1, PIF-binding, PIFtide, PS 210, PS210, PS-210, PS423, S6K

Product Description

PS210 is a potent and selective PDK1 activator (Kd: 3 µM) that binds its PIF pocket without affecting kinases like S6K or Akt. Its prodrug, PS423, acts as a substrate-selective cellular PDK1 inhibitor, blocking S6K phosphorylation. These compounds are valuable research tools for studying PDK1-dependent signaling pathways in cancer and metabolic disease models.

Product Properties

• Molecular Weight: 380.31
• Purity: 99.78% (May vary between batches)
• CAS Number: [1221962-86-2]
• Formula: C19H15F3O5
• Target: PDK

Application Notes

• Application Notes: Solubility: DMSO:60 mg/mL (157.77 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM)