Auristatin E is a potent microtubule-disrupting cytotoxin that inhibits tubulin polymerization, arresting cell division. As the payload (MMAE) in antibody-drug conjugates, it is widely used in oncology research for evaluating antitumor efficacy in both in vitro and in vivo models.
Molecular Weight:
732.01
Purity:
98.81% (May vary between batches)
CAS Number:
[160800-57-7]
Formula:
C40H69N5O7
Target:
ADC Cytotoxin,Microtubule Associated
Application Notes:
Solubility: DMSO:60 mg/mL (81.97 mM)
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