Allitinib, CAS [[897383-62-9]]
Catalog Number:
BYT-ORB1308633
Product Overview
Article Name:
Allitinib, CAS [[897383-62-9]]
Biozol Catalog Number:
BYT-ORB1308633
Supplier Catalog Number:
orb1308633
Alternative Catalog Number:
BYT-ORB1308633-1, BYT-ORB1308633-1, BYT-ORB1308633-10, BYT-ORB1308633-100, BYT-ORB1308633-25, BYT-ORB1308633-5, BYT-ORB1308633-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
HER1, Epidermal growth factor receptor, EGFRL858R/T790M, EGFR (T790M/L858R), EGFR, ErbB4, ErbB2, ErbB-1, Irreversible, inhibit, Inhibitor, ALS1306, ALS-1306, Allitinib, anti-cancer, ALS 1306, anilino-quinazoline, AST 1306, AST1306, AST-1306
Product Description
Allitinib (AST-1306) is an irreversible, potent inhibitor of EGFR and ErbB2, exhibiting IC50 values of 0.5 nM and 3 nM, respectively. This small molecule is utilized in cancer research, demonstrating antitumor efficacy in both cellular assays and in vivo models of various carcinomas.
Product Properties
Molecular Weight:
448.88
Purity:
99.91% (May vary between batches)
CAS Number:
[897383-62-9]
Formula:
C24H18ClFN4O2
Target:
EGFR
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.46 mM),DMSO:55 mg/mL (122.53 mM)
