Edgeworin is a small molecule inhibitor of DNA polymerase beta (pol beta), blocking both its lyase and polymerase activities. This inhibition of base excision repair potentiates bleomycins cytotoxicity in vitro, making it a research tool for studying DNA repair mechanisms and combination therapies in cancer models.
Molecular Weight:
322.272
CAS Number:
[120028-43-5]
Formula:
C18H10O6
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