Rocaglaol is a potent small molecule with anticancer activity, inducing apoptosis via the mitochondrial pathway and causing G2/M arrest through Cdc25C/Cdc2 modulation. It also exhibits neuroprotective effects in vivo by inhibiting NF-kappaB/AP-1 and can mitigate chemotherapy-induced cardiotoxicity. Furthermore, it and related compounds strongly inhibit protein synthesis and cell growth in vitro at low ng/mL concentrations.
Molecular Weight:
434.48
CAS Number:
[147059-46-9]
Formula:
C26H26O6
Target:
Apoptosis
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