AS601245.2TFA (345987-15-7 free base) is a potent, cell-permeable inhibitor of JNK isoforms, with IC50 values of 150 nM (hJNK1), 220 nM (hJNK2), and 70 nM (hJNK3). This compound is widely used in research to investigate JNK signaling pathways in cellular models of apoptosis, inflammation, and neurological disorders.
Molecular Weight:
600.50
CAS Number:
[345987-16-8]
Formula:
C24H18F6N6O4S
Target:
JNK
Application Notes:
Solubility: DMSO:60 mg/mL (99.92 mM)
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