SYN1143, CAS [[913376-84-8]]

Product Overview

• Article Name: SYN1143, CAS [[913376-84-8]]
• Biozol Catalog Number: BYT-ORB1685385
• Supplier Catalog Number: orb1685385
• Alternative Catalog Number: BYT-ORB1685385-1, BYT-ORB1685385-10, BYT-ORB1685385-25, BYT-ORB1685385-5, BYT-ORB1685385-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: SYN 1143, SYN1143, SYN-1143, RON-IN-1, RON, tumor, inhibit, Inhibitor, HGFR, cancer, AMG 1, AMG1, AMG-1, c-Met/HGFR, cMet, c-Met, cMet/HGFR, dual

Product Description

SYN1143 (AMG-1) is a highly potent small molecule inhibitor targeting the RON and c-Met receptor tyrosine kinases, exhibiting in vitro IC50 values of 9 nM and 4 nM, respectively. This compound is a valuable research tool for investigating cancer cell signaling, proliferation, and metastasis in both cellular and animal models of various malignancies.

Product Properties

• Molecular Weight: 556.58
• Purity: 99.69% (May vary between batches)
• CAS Number: [913376-84-8]
• Formula: C31H29FN4O5
• Target: c-Met/HGFR

Application Notes

• Application Notes: Solubility: DMSO:90 mg/mL (161.7 mM)