Upadacitinib is a potent, selective JAK1 inhibitor with approximately 74-fold selectivity over JAK2 in cellular cytokine assays. It has demonstrated efficacy in rat models of arthritis and is widely used in research on autoimmune and inflammatory diseases, including in vitro mechanistic studies and in vivo preclinical models.
Molecular Weight:
602.521
CAS Number:
[1607431-21-9]
Formula:
C21H33F3N6O11
Target:
JAK,Others
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