MK-2048 is a potent small molecule inhibitor of HIV-1 integrase, demonstrating high in vitro potency with IC50 values of 2.6 nM against wild-type IN and 1.5 nM against the INR263K mutant. This compound is a valuable research tool for studying integrase function and resistance mechanisms in both biochemical and cell-based antiviral assays.
Molecular Weight:
461.87
CAS Number:
[869901-69-9]
Formula:
C21H21ClFN5O4
Target:
HIV Protease,Integrase
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