AZD0780, CAS [[2455427-91-3]]

Product Overview

• Article Name: AZD0780, CAS [[2455427-91-3]]
• Biozol Catalog Number: BYT-ORB1685685
• Supplier Catalog Number: orb1685685
• Alternative Catalog Number: BYT-ORB1685685-1, BYT-ORB1685685-1, BYT-ORB1685685-10, BYT-ORB1685685-100, BYT-ORB1685685-200, BYT-ORB1685685-25, BYT-ORB1685685-5, BYT-ORB1685685-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: AZD 0780, AZD0780, AZD-0780, PCSK9, PCSK9-IN-12, EX-A 6975, EX-A6975, EX-A-6975

Product Description

AZD0780 is an orally bioavailable small molecule PCSK9 inhibitor that binds the C-terminal domain of PCSK9. It disrupts lysosomal trafficking of the PCSK9-LDLR complex to prevent LDL receptor degradation, making it a valuable research tool for investigating hypercholesterolemia in both cellular and animal models.

Product Properties

• Molecular Weight: 414.41
• Purity: 99.74% (May vary between batches)
• CAS Number: [2455427-91-3]
• Formula: C20H20F2N6O2
• Target: Others

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.96 mM),DMSO:247.5 mg/mL (597.23 mM)