Bexotegrast, CAS [[2376257-44-0]]

Product Overview

• Article Name: Bexotegrast, CAS [[2376257-44-0]]
• Biozol Catalog Number: BYT-ORB1690953
• Supplier Catalog Number: orb1690953
• Alternative Catalog Number: BYT-ORB1690953-1, BYT-ORB1690953-1, BYT-ORB1690953-10, BYT-ORB1690953-25, BYT-ORB1690953-5, BYT-ORB1690953-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: PLN-74809, alphaVbeta6 integrin, alphaVbeta1 integrin, Bexotegrast

Product Description

Bexotegrast (PLN-74809) is a potent, orally bioavailable dual inhibitor of alphavbeta6 and alphavbeta1 integrins that blocks TGF-beta activation. Its antifibrotic properties are being investigated in preclinical and clinical research for fibrotic lung diseases, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Product Properties

• Molecular Weight: 492.61
• Purity: 99.53% (May vary between batches)
• CAS Number: [2376257-44-0]
• Formula: C27H36N6O3
• Target: Integrin

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.12 mM),DMSO:100 mg/mL (203 mM)