MS98 is a potent and selective PROTAC that induces degradation of total AKT (pan-AKT1/2/3) with a DC50 of 78 nM, exhibiting high-affinity binding to AKT isoforms. This degrader is a valuable chemical tool for probing AKT-dependent signaling in cancer research, applicable in both cellular and in vivo models to study oncogenesis and therapeutic resistance.
Molecular Weight:
1097.86
CAS Number:
[2376137-31-2]
Formula:
C58H81ClN10O7S
Target:
Others,Akt,PROTACs
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