MS170 is a potent and specific PROTAC AKT degrader with a DC50 of 32 nM for total AKT reduction. It binds AKT1, AKT2, and AKT3 with high affinity (Kd values of 1.3, 77, and 6.5 nM, respectively). This tool compound is useful for investigating AKT signaling in cancer research models, both in vitro and in vivo.
Molecular Weight:
870.45
CAS Number:
[2376136-61-5]
Formula:
C45H56ClN9O7
Target:
Akt,PROTACs
* VAT and and shipping costs not included. Errors and price changes excepted
