Zeteletinib hemiadipate, CAS [[2375837-06-0]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB1690958
Supplier Catalog Number:
orb1690958
Alternative Catalog Number:
BYT-ORB1690958-5
Manufacturer:
Biorbyt
Category:
Biochemikalien
Zeteletinib hemiadipate (BOS-172738, DS-5010) is a potent and selective oral RET kinase inhibitor with nanomolar activity, showing high selectivity over VEGFR2. It effectively targets wild-type RET, gatekeeper mutants (V804M/L), and the oncogenic M918T variant. This compound has demonstrated significant antitumor efficacy in both cellular assays and in vivo models, supporting its investigation in RET-driven cancers.
Molecular Weight:
1147.098
CAS Number:
[2375837-06-0]
Formula:
C56H56F6N8O12
Target:
c-RET,PDGFR,Others
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