XZ739 is a potent, Cereblon-dependent PROTAC that selectively degrades BCL-XL, inducing caspase-mediated apoptosis. It demonstrates high potency with a DC50 of 2.5 nM in MOLT-4 cells and is a valuable chemical probe for studying apoptosis and BCL-2 family biology in cancer research.
Molecular Weight:
1349.99
CAS Number:
[2365172-19-4]
Formula:
C65H76ClF3N8O12S3
Target:
Apoptosis,PROTACs,Bcl-2 Family
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