Ipivivint is a potent, orally active first-in-class inhibitor of CDC-like kinases (CLK1/2/3). It suppresses Wnt signaling by inhibiting CLK activity, reducing SRSF phosphorylation, and disrupting spliceosome function. This compound is a valuable research tool for studying cancer mechanisms in both in vitro and in vivo models.
Molecular Weight:
464.5
CAS Number:
[1481617-15-5]
Formula:
C26H21FN8
Target:
Wnt/beta-catenin,CDK,Others
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