CAY10561 is a potent and selective ATP-competitive inhibitor of ERK2 (Ki=2 nM), a key kinase in the MAPK pathway constitutively active in many cancers. It inhibits proliferation in cellular models like COLO 205 cells (IC50=0.54 µM) and is a valuable tool for studying ERK-driven processes in oncology research.
Molecular Weight:
459.3
CAS Number:
[933786-58-4]
Formula:
C22H17Cl2FN4O2
Target:
ERK,Others
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