This potent and selective allosteric HDAC3 inhibitor exhibits a Ki of 0.16 nM and demonstrates significant selectivity in both enzymatic and cellular assays. It shows preferential activity against acute myeloid and monocytic leukemia cell lines, making it a valuable chemical probe for epigenetic research in oncology, particularly for studying HDAC3-specific roles in hematological malignancies.
Molecular Weight:
337.42
CAS Number:
[2044701-99-5]
Formula:
C20H23N3O2
Target:
Others,HDAC
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