PKI-402 is a highly potent dual inhibitor of PI3K and mTOR, demonstrating low nanomolar IC50 values against key isoforms including PI3Kalpha (2 nM) and mTOR (3 nM). It is a valuable research tool for investigating the PI3K/Akt/mTOR signaling pathway in cancer and other diseases, with utility in both in vitro and in vivo experimental models.
Molecular Weight:
570.65
Purity:
>99.99% (May vary between batches)
CAS Number:
[1173204-81-3]
Formula:
C29H34N10O3
Target:
PI3K,mTOR
Application Notes:
Solubility: DMSO:5 mg/mL (8.76 mM)
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