IL-4-inhibitor-1, CAS [[1332184-63-0]]

Product Overview

• Article Name: IL-4-inhibitor-1, CAS [[1332184-63-0]]
• Biozol Catalog Number: BYT-ORB1693654
• Supplier Catalog Number: orb1693654
• Alternative Catalog Number: BYT-ORB1693654-1, BYT-ORB1693654-1, BYT-ORB1693654-10, BYT-ORB1693654-100, BYT-ORB1693654-25, BYT-ORB1693654-5, BYT-ORB1693654-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: IL4inhibitor1, IL-4-inhibitor-1, IL-4, ILReceptor, IL Receptor, IL 4 inhibitor 1

Product Description

This small molecule IL-4 inhibitor selectively binds IL-4 (Kd = 1.8 µM) to block the IL-4/JAK1/STAT6 signaling pathway, as demonstrated by its inhibition of IL-4-induced STAT6 phosphorylation in THP-1 cells. It is a valuable research tool for studying type 2 immune responses in asthma and allergy models, both in vitro and in vivo.

Product Properties

• Molecular Weight: 321.31
• Purity: >99.99% (May vary between batches)
• CAS Number: [1332184-63-0]
• Formula: C18H12FN3O2
• Target: Interleukin,IL Receptor

Application Notes

• Application Notes: Solubility: Ethanol:10 mg/mL (31.12 mM),DMF:27 mg/mL (84.03 mM),DMSO:PBS (pH 7.2) (1:5):0.1 mg/mL (0.31 mM),DMSO:50 mg/mL (155.61 mM)