CMC2.24 is an orally bioavailable tricarbonylmethane compound that inhibits Ras/ERK signaling and zinc-dependent MMPs. It has demonstrated in vivo efficacy in suppressing pancreatic tumorigenesis in mice and shows potential in osteoarthritis models by modulating the NF-kappaB/HIF-2alpha pathway to protect cartilage.
Molecular Weight:
427.45
CAS Number:
[1255639-43-0]
Formula:
C26H21NO5
Target:
Apoptosis,MMP,Others,Ras
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