FR 167356, FR167356, FR-167356, Vacuolar type H+-ATPase
FR-167356 is a potent and selective inhibitor of the a3 isoform of vacuolar H-ATPase, demonstrating activity in osteoclast, renal, and macrophage membranes. This compound has been shown to reduce bone metastasis in B16-F10 melanoma models, making it a useful research tool for studying bone biology and cancer metastasis.
Molecular Weight:
378.25
Purity:
99.74% (May vary between batches)
CAS Number:
[174185-16-1]
Formula:
C19H17Cl2NO3
Target:
ATPase,Proton pump
Application Notes:
Solubility: DMSO:22.5 mg/mL (59.48 mM)
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