TFC-007 is a potent and selective inhibitor of hematopoietic prostaglandin D synthase (H-PGDS), effectively suppressing inflammatory mediators. It serves as a key precursor for synthesizing H-PGDS-targeting PROTAC degraders and has been utilized in research models, such as cedar pollen-induced allergic rhinitis in guinea pigs, to study allergic inflammation pathways.
Molecular Weight:
487.55
Purity:
98.07% (May vary between batches)
CAS Number:
[927878-49-7]
Formula:
C27H29N5O4
Target:
Ligands for Target Protein for PROTAC,PGE Synthase,Ligands for E3 Ligase
Application Notes:
Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble)
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