Inhibitor, inhibit, K562, STAT5beta, STAT5b, Stafib 1, Stafib1, Stafib-1, STAT
Stafib-1 is a potent and selective STAT5beta inhibitor that targets its SH2 domain, exhibiting an IC50 of 154 nM and a Ki of 44 nM. This small molecule is a valuable research tool for studying STAT5beta-dependent signaling in cancer and hematopoiesis, with utility in both in vitro and in vivo experimental models.