This metabolite of the anticancer agent methotrexate acts as a dual inhibitor of thymidylate synthase and GAR transformylase, enzymes critical for nucleotide synthesis. It is consequently a valuable tool for in vitro studies in oncology and biochemistry research, particularly for investigating antifolate mechanisms.
Molecular Weight:
471.43
CAS Number:
[28459-40-7]
Formula:
C20H21N7O7
Target:
Others,Endogenous Metabolite
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