TCO-NHS ester is an alkyl/ether linker used to construct PROTAC molecules for targeted protein degradation. It covalently links a target-binding ligand to an E3 ligase recruiter, enabling the study of protein function in both cellular and in vivo models via the ubiquitin-proteasome system.
Molecular Weight:
267.28
Purity:
99.86% (May vary between batches)
CAS Number:
[1191901-33-3]
Formula:
C13H17NO5
Target:
PROTAC Linker
Application Notes:
Solubility: DMSO:150 mg/mL (561.21 mM)
* VAT and and shipping costs not included. Errors and price changes excepted