SPR inhibitor 3 is a potent small molecule targeting sepiapterin reductase (SPR), effectively reducing tetrahydrobiopterin (BH4) levels. It demonstrates high in vitro affinity (IC50=74 nM) and cellular activity (IC50=5.2 µM), underpinning its utility in researching neuropathic and inflammatory pain mechanisms in both cellular and animal models.
Molecular Weight:
262.3
CAS Number:
[1292285-54-1]
Formula:
C14H18N2O3
Target:
Others
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