RO 4938581 is a potent and selective GABAA alpha5 inverse agonist, exhibiting high affinity for alpha5beta3gamma2 receptors (Ki = 4.6 nM) with significant selectivity over alpha1, alpha2, and alpha3 subtypes. This compound is a valuable research tool for investigating the role of alpha5-containing GABAA receptors in cognitive processes, supporting both in vitro and in vivo experimental studies.
Molecular Weight:
352.14
CAS Number:
[883093-10-5]
Formula:
C13H8BrF2N5
Target:
GABA Receptor
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