Rhosin is a potent and selective small molecule inhibitor of RhoA subfamily GTPases, binding specifically to RhoA (Kd ~0.4 µM) to disrupt RhoA-GEF interactions. It has been utilized in vitro to study RhoA-mediated cytoskeletal dynamics and cell adhesion, and has shown efficacy in inducing apoptosis in various cancer cell lines.
Molecular Weight:
358.4
CAS Number:
[1173671-63-0]
Formula:
C20H18N6O
Target:
Apoptosis,Rho,Ras
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