LTE4, LTC4, LTD4, NID 525, NID525, NID-525, LeukotrieneReceptor, leukotriene D (LTD), Leukotriene Receptor, CYP3A4, PPARgamma, RG12525, RG-12525, RG 12525
RG-12525 is a potent, orally active antagonist of cysteinyl leukotriene receptors and an agonist of PPAR-gamma, with species-specific utility for asthma research. It demonstrates nanomolar potency in inhibiting ligand-induced contractions in vitro and also modulates CYP3A4 activity.