Poloxime is a non-ATP-competitive inhibitor of Polo-like kinase 1 (Plk1), derived from the hydrolysis of poloxin. It exhibits moderate inhibitory activity and serves as a useful chemical probe for studying cell cycle regulation and anti-mitotic mechanisms in both cellular and biochemical assays.
Molecular Weight:
179.22
CAS Number:
[17302-61-3]
Formula:
C10H13NO2
Target:
PLK
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