Picrotoxinin, CAS [[17617-45-7]]

Product Overview

• Article Name: Picrotoxinin, CAS [[17617-45-7]]
• Biozol Catalog Number: BYT-ORB1706790
• Supplier Catalog Number: orb1706790
• Alternative Catalog Number: BYT-ORB1706790-10, BYT-ORB1706790-25
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: GABAA, GABA Receptor, GABAReceptor, chloride channel, Chloride channel, Chloridechannel, Picrotoxinin

Product Description

Picrotoxinin is a noncompetitive GABAA receptor antagonist that blocks chloride channels, exhibiting an IC50 of 1.15 µM for the alpha1beta2gamma2L subtype. This convulsant agent is widely used in neuroscience research to study inhibitory neurotransmission, synaptic plasticity, and seizure mechanisms in both in vitro and in vivo experimental models.

Product Properties

• Molecular Weight: 292.28
• Purity: 99.97% (May vary between batches)
• CAS Number: [17617-45-7]
• Formula: C15H16O6
• Target: Chloride channel,GABA Receptor

Application Notes

• Application Notes: Solubility: DMSO:90 mg/mL (307.92 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.29 mM)