Apratastat is a potent, orally bioavailable dual inhibitor of TACE and MMPs, effectively suppressing TNF-alpha release. It demonstrates significant activity in vitro, ex vivo, and in vivo models, making it a valuable research tool for studying inflammatory and autoimmune diseases, cancer, and tissue remodeling processes.
Molecular Weight:
414.5
CAS Number:
[287405-51-0]
Formula:
C17H22N2O6S2
Target:
MMP,TNF
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