Alrizomadlin, CAS [[1818393-16-6]]

Product Overview

• Article Name: Alrizomadlin, CAS [[1818393-16-6]]
• Biozol Catalog Number: BYT-ORB1707648
• Supplier Catalog Number: orb1707648
• Alternative Catalog Number: BYT-ORB1707648-1,BYT-ORB1707648-10,BYT-ORB1707648-100,BYT-ORB1707648-25,BYT-ORB1707648-5,BYT-ORB1707648-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: AA 115, AA115, AA-115, APG 115, APG115, APG-115, Alrizomadlin, Mdm2

Product Description

Alrizomadlin (APG-115) is an orally bioavailable MDM2-p53 interaction inhibitor. It demonstrates potent, dose-dependent anti-proliferative activity in TP53 wild-type AML cell lines such as MOLM-13 and induces p53-dependent cell cycle arrest and apoptosis, supporting its investigation in cancer research.

Product Properties

• Molecular Weight: 642.59
• Purity: 99.47% (May vary between batches)
• CAS Number: [1818393-16-6]
• Formula: C34H38Cl2FN3O4
• Target: Apoptosis,MDM-2/p53,E1/E2/E3 Enzyme,Mdm2

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.78 mM),DMSO:81.67 mg/mL (127.1 mM)