AMG-1694, CAS [[1361217-07-3]]

Product Overview

• Article Name: AMG-1694, CAS [[1361217-07-3]]
• Biozol Catalog Number: BYT-ORB1707669
• Supplier Catalog Number: orb1707669
• Alternative Catalog Number: BYT-ORB1707669-1,BYT-ORB1707669-10,BYT-ORB1707669-100,BYT-ORB1707669-200,BYT-ORB1707669-25,BYT-ORB1707669-5,BYT-ORB1707669-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: AMG1694, AMG-1694, AMG 1694, GK-GKRP

Product Description

AMG-1694 is a potent small molecule disruptor of the GK-GKRP complex with an IC50 of 7 nM. It indirectly activates glucokinase, reverses GKRP-mediated inhibition, and promotes GK translocation. This compound effectively normalizes blood glucose in diabetic rodent models without inducing hypoglycemia in normoglycemic animals, making it a valuable research tool for studying type 2 diabetes pathways.

Product Properties

• Molecular Weight: 533.63
• Purity: 98.37% (May vary between batches)
• CAS Number: [1361217-07-3]
• Formula: C23H30F3N3O4S2
• Target: Glucokinase

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.75 mM),DMSO:50 mg/mL (93.7 mM)