AMD 3465 is a potent and selective CXCR4 antagonist, inhibiting X4-tropic HIV-1 replication with low nanomolar IC50 values while being inactive against R5 viruses. It blocks CXCR4 ligand and antibody binding and is a valuable research tool for studying CXCR4 function in cancer metastasis, stem cell mobilization, and HIV entry in vitro.
Molecular Weight:
410.60
CAS Number:
[185991-24-6]
Formula:
C24H38N6
Target:
HIV Protease,CXCR
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